1,4-Benzenediamine

物化性质

外观与性状：

白色至淡紫色固体

密度：

1.15 g/cm3

熔点：

139 °C

沸点：

267 °C(lit.)

闪点：

156 °C

水溶解性：

47 g/L (25 ºC)

折射率：

1.66

蒸汽压：

0.00817mmHg at 25°C

蒸汽密度：

3.7 (vs air)

存储条件/存储方法：

库房通风低温干燥,与氧化剂、食品添加剂分开存放

稳定性相关：

1.有毒。其毒性与邻苯二胺基本相同。家兔口服致死量250mg/kg。详见邻苯二胺。

2.可经皮肤吸收或吸入粉尘而引起中毒，经皮肤吸收引起的中毒现象居多。它对皮肤的反应各不相同，急性严重的发疹性湿疹可达到背部、面部和腹部，并且有类似丹毒的痂皮。其粉尘对呼吸道的作用也各不相同，可以引起鼻炎、支气管炎、经常发烧、特有的喘息以及由于气管炎症而引起的迷走神经的紧张等症状。对家兔，经口最低致死量为300mg/kg。工作场所对苯二胺的最高容许浓度为0.1mg/m3。

3.稳定性^[19] 稳定

4.禁配物^[20] 强氧化剂、酸类、酰基氯、酸酐、氯仿

5.避免接触的条件^[21] 受热

6.聚合危害^[22] 不聚合

其它信息：

1.性状：白色至淡紫红色晶体。^[1]

2.熔点（℃）：145~147^[2]

3.沸点（℃）：267^[3]

4.相对蒸气密度（空气=1）：3.7^[4]

5.饱和蒸气压（kPa）：0.14（100℃）^[5]

6.临界压力（MPa）：5.18^[6]

7.辛醇/水分配系数：-0.25~-0.7^[7]

8.闪点（℃）：155^[8]

9.爆炸上限（%）：9.8^[9]

10.爆炸下限（%）：1.3^[10]

11.溶解性：微溶于水，溶于乙醇、乙醚、苯、氯仿、丙酮。^[11]

安全信息

外观与性状：

白色至淡紫色固体

密度：

1.15 g/cm3

熔点：

139 °C

沸点：

267 °C(lit.)

闪点：

156 °C

水溶解性：

47 g/L (25 ºC)

折射率：

1.66

蒸汽压：

0.00817mmHg at 25°C

蒸汽密度：

3.7 (vs air)

存储条件/存储方法：

库房通风低温干燥,与氧化剂、食品添加剂分开存放

稳定性相关：

1.有毒。其毒性与邻苯二胺基本相同。家兔口服致死量250mg/kg。详见邻苯二胺。

2.可经皮肤吸收或吸入粉尘而引起中毒，经皮肤吸收引起的中毒现象居多。它对皮肤的反应各不相同，急性严重的发疹性湿疹可达到背部、面部和腹部，并且有类似丹毒的痂皮。其粉尘对呼吸道的作用也各不相同，可以引起鼻炎、支气管炎、经常发烧、特有的喘息以及由于气管炎症而引起的迷走神经的紧张等症状。对家兔，经口最低致死量为300mg/kg。工作场所对苯二胺的最高容许浓度为0.1mg/m3。

3.稳定性^[19] 稳定

4.禁配物^[20] 强氧化剂、酸类、酰基氯、酸酐、氯仿

5.避免接触的条件^[21] 受热

6.聚合危害^[22] 不聚合

其它信息：

1.性状：白色至淡紫红色晶体。^[1]

2.熔点（℃）：145~147^[2]

3.沸点（℃）：267^[3]

4.相对蒸气密度（空气=1）：3.7^[4]

5.饱和蒸气压（kPa）：0.14（100℃）^[5]

6.临界压力（MPa）：5.18^[6]

7.辛醇/水分配系数：-0.25~-0.7^[7]

8.闪点（℃）：155^[8]

9.爆炸上限（%）：9.8^[9]

10.爆炸下限（%）：1.3^[10]

11.溶解性：微溶于水，溶于乙醇、乙醚、苯、氯仿、丙酮。^[11]

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :

SS8050000

CHEMICAL NAME :

p-Phenylenediamine

CAS REGISTRY NUMBER :

106-50-3

LAST UPDATED :

199712

DATA ITEMS CITED :

80

MOLECULAR FORMULA :

C6-H8-N2

MOLECULAR WEIGHT :

108.16

WISWESSER LINE NOTATION :

ZR DZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Human

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - mouse

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Mammal - dog

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Mammal - pig

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - guinea pig

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - man

DOSE/DURATION :

71 mg/kg

TOXIC EFFECTS :

Behavioral - muscle weakness Lungs, Thorax, or Respiration - acute pulmonary edema Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

80 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

920 mg/m3/4H

TOXIC EFFECTS :

Behavioral - general anesthetic Gastrointestinal - nausea or vomiting Kidney, Ureter, Bladder - hematuria

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

37 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

170 mg/kg

TOXIC EFFECTS :

Cardiac - pulse rate increase, without fall in BP Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - respiratory stimulation

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

50 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Unreported

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

133 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

100 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

50 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

140 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Unreported

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

331 mg/kg

TOXIC EFFECTS :

Brain and Coverings - other degenerative changes

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

100 mg/kg

TOXIC EFFECTS :

Behavioral - coma Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - nausea or vomiting

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

17 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - cat

DOSE/DURATION :

100 mg/kg

TOXIC EFFECTS :

Cardiac - pulse rate increase, without fall in BP Lungs, Thorax, or Respiration - respiratory stimulation Nutritional and Gross Metabolic - body temperature decrease

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

250 mg/kg

TOXIC EFFECTS :

Cardiac - pulse rate increase, without fall in BP Lungs, Thorax, or Respiration - respiratory stimulation Nutritional and Gross Metabolic - body temperature decrease

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

5 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

150 mg/kg

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

200 mg/kg

TOXIC EFFECTS :

Cardiac - pulse rate increase, without fall in BP Lungs, Thorax, or Respiration - respiratory stimulation Nutritional and Gross Metabolic - body temperature decrease

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

300 mg/kg

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - changes in structure or function of salivary glands

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

145 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Unreported

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

145 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Bird - quail

DOSE/DURATION :

100 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Bird - wild bird species

DOSE/DURATION :

100 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

1050 mg/kg/30W-I

TOXIC EFFECTS :

Brain and Coverings - recordings from specific areas of CNS Behavioral - alteration of classical conditioning Liver - fatty liver degeneration

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

28 gm/kg/80W-C

TOXIC EFFECTS :

Endocrine - changes in spleen weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

16800 mg/kg/12W-C

TOXIC EFFECTS :

Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

105 mg/kg/30W-I

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Liver - fatty liver degeneration Liver - liver function tests impaired

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2625 mg/kg/30W-C

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :

Sex chromosome loss and nondisjunction

TYPE OF TEST :

DNA inhibition

MUTATION DATA

TYPE OF TEST :

Cytogenetic analysis

TEST SYSTEM :

Rodent - hamster Ovary

REFERENCE :

EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 27,67,1996 *** REVIEWS *** ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 0.1 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,125,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,125,1978 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 4(3),203,1985 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.1 mg/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,205,1971 OSHA PEL (Gen Indu):8H TWA 0.1 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.1 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.1 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.1 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.1 mg/m3;Skin JAN 1993 OEL-BELGIUM:TWA 0.1 mg/m3;Skin JAN 1993 OEL-DENMARK:TWA 0.1 mg/m3;Skin JAN 1993 OEL-FINLAND:TWA 0.1 mg/m3;STEL 0.3 mg/m3;Skin JAN 1993 OEL-FRANCE:TWA 0.1 mg/m3;Skin JAN 1993 OEL-GERMANY:TWA 0.1 mg/m3;Skin JAN 1993 OEL-THE NETHERLANDS:TWA 0.1 mg/m3;Skin JAN 1993 OEL-THE PHILIPPINES:TWA 0.1 mg/m3;Skin JAN 1993 OEL-POLAND:TWA 0.1 mg/m3 JAN 1993 OEL-RUSSIA:STEL 0.05 mg/m3 JAN 1993 OEL-SWEDEN:TWA 0.1 mg/m3;STEL 0.3 mg/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 0.1 mg/m3;STEL 0.2 mg/m3;Skin JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 mg/m3;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO p-PHENYLENE DIAMINE-air:10H TWA 0.1 mg/m3 (Sk)REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 56950 No. of Facilities: 2017 (estimated) No. of Industries: 9 No. of Occupations: 11 No. of Employees: 14983 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 56950 No. of Facilities: 5390 (estimated) No. of Industries: 6 No. of Occupations: 7 No. of Employees: 49939 (estimated) No. of Female Employees: 37209 (estimated)

毒理学数据：

1.急性毒性^[12] LD50：80mg/kg（大鼠经口）

2.刺激性^[13] 人经皮：250mg（24h），轻度刺激。

3.致突变性^[14] 微生物致突变性：鼠伤寒沙门菌2μmol/皿。DNA抑制：小鼠经口200mg/kg。细胞遗传学分析：仓鼠卵巢15mg/L。性染色体缺失和不分离：黑腹果蝇经口15500μmol/L（3d）。

4.致癌性^[15] IARC致癌性评论：G3，对人及动物致癌性证据不足。

生态数据：

1.生态毒性^[16]

LC50：5.74mg/L（48h）（金鱼）

EC50：74mg/L（60h）（梨形四膜虫）；37mg/L（30min）（发光菌，Microtox毒性测试）

2.生物降解性^[17]

好氧生物降解（h）：168~672

厌氧生物降解（h）：672~2688

3.非生物降解性^[18]

光解最大光吸收-高（nm）：308

水中光氧化半衰期（h）：30~1740

空气中光氧化半衰期（h）：0.28~2.8

MSDS

国标编号:	61789
ＣＡＳ:	106-50-3
中文名称:	1，4-苯二胺
英文名称:	p-Phenylenediamine；1,4-diaminobenzene
别 名:	对苯二胺；1，4-二氨基苯；乌尔丝D
分子式:	C6H8N2；NH2C6H4NH2
分子量:	108.14
熔 点:	147℃ 沸点：267℃
密 度:	相对密度(空气=1)3.7
蒸汽压:	68℃
溶解性:	溶于水、乙醇、乙醚、氯仿、苯
稳定性:	稳定
外观与性状:	白色至淡紫红色晶体
危险标记:	15(毒害品)
用 途:	作为染料中间体，环氧树脂固化剂及橡胶防老剂DNP、DBP等的生产

2.对环境的影响:
一、健康危害
侵入途径：吸入、食入、经皮吸收。
健康危害：不易因吸入而中毒。如经口进入 ，则毒作用与苯胺同。对苯二胺有很强烈的致敏作用。引起接触性皮炎、湿疹、支气管哮喘。
二、毒理学资料及环境行为
急性毒性：LD5080mg/kg(大鼠经口)
致突变性：微生物致突变性：鼠伤寒沙门氏菌2umol/皿。DNA抑制：小鼠经口200mg/kg。
致癌性：IARC致癌性评论：动物不明确。
危险特性：遇明火、高热可燃。与强氧化剂可发生反应。受热分解放出有毒的氧化氮烟气。
燃烧(分解)产物：一氧化碳、二氧化碳、氧化氮。
3.现场应急监测方法:
　
4.实验室监测方法:
苯胺法《化工企业空气中有害物质测定方法》，化学工业出版社
5.环境标准:
美国 车间卫生标准 0.1mg/m3[皮]
前苏联(1975) 水体中有害有机物的最大允许浓度 0.1mg/L
前苏联(1975)污水排放标准 5mg/L
6.应急处理处置方法:
一、泄漏应急处理
隔离泄漏污染区，周围设警告标志，建议应急处理人员戴好防毒面具，穿化学防护服。不要直接接触泄漏物，用清洁的铲子收集于干燥净洁有盖的容器中，运至废物处理场所或用沙土混合，逐渐倒入稀盐酸中(1体积浓盐酸加2体积水稀释)，放置24小时，然后废弃。如大量泄漏，收集回收或无害处理后废弃。
废弃物处置方法：用控制焚烧法，焚烧炉排气中的氮氧化物通过洗涤器或高温装置除去。
二、防护措施
呼吸系统防护：空气中浓度较高时，佩带防毒面具。紧急事态抢救或逃生时，应该佩戴自给式呼吸器。
眼睛防护：戴化学安全防护眼镜。
防护服：穿紧袖工作服，长统胶鞋。
手防护：戴橡皮手套。
其它：工作现场禁止吸烟、进食和饮水。及时换洗工作服。工作前后不饮酒，用温水洗澡。进行就业前和定期的体检。
三、急救措施
皮肤接触：立即脱去污染的衣着，用肥皂水及清水彻底冲洗。
眼睛接触：立即提起眼睑，用大量流动清水或生理盐水冲洗。
吸入：迅速脱离现场至空气新鲜处。保持呼吸道通畅。必要时进行人工呼吸。就医。
食入：误服者给漱口，饮水，洗胃后口服活性炭，再给以导泻。就医。
灭火方法：雾状水、二氧化碳、砂土、干粉、泡沫。

海关数据

中国海关编码：2921519090

概述：

2921519090. 间-、对-苯二胺、二氨基甲苯等〔包括衍生物及它们的盐〕. 增值税率:17.0%. 退税率:17.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

申报要素：

品名, 成分含量, 用途

摘要/Summary：

2921519090. o-, m-, p-phenylenediamine, diaminotoluenes, and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:17.0%. . MFN tariff:6.5%. General tariff:30.0%

分子结构与计算化学数据

分子结构数据

1、摩尔折射率：34.72

2、摩尔体积（cm³/mol）：93.9

3、等张比容（90.2K）：258.9

4、表面张力（dyne/cm）：57.5

5、介电常数：

6、偶极距（10^-24cm³）：

7、极化率：13.76

计算化学数据

1.疏水参数计算参考值（XlogP）:无

2.氢键供体数量:2

3.氢键受体数量:2

4.可旋转化学键数量:0

5.互变异构体数量:无

6.拓扑分子极性表面积52

7.重原子数量:8

8.表面电荷:0

9.复杂度:54.9

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1