5-Benzofuranmethanol, a-[2-(4-hydroxyphenyl)ethyl]-4,7-dimethoxy-6-[2-(1-piperidinyl)ethoxy]-
- 中文别名：哌丙呋罗
- 中文释义：哌丙呋罗
- 英文别名：4-[3-[4,7-dimethoxy-6-(2-piperidin-1-ylethoxy)-1-benzofuran-5-yl]-3-hydroxypropyl]phenol;
EINECS 255-035-6;
Piprofurol;
Piprofurol [INN];
Piprofurolum;
Piprofurolum [INN-Latin];
1-[4,7-dimethoxy-6-(2-piperidin-1-yl-ethoxy)-benzofuran-5-yl]-3-(4-hydroxy-phenyl)-propan-1-ol
- CAS No.：40680-87-3
- 分子式：C26H33NO6
- 分子量：0
- 精确分子量：455.23100
- PSA：84.53000
- InChI：The Key: LIAPJIQUUKLLDZ-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.214g/cm3
- 沸点：
- 640.7ºC at 760 mmHg
- 闪点：
- 341.3ºC
- 折射率：
- 1.596
安全信息
- 密度：
- 1.214g/cm3
- 沸点：
- 640.7ºC at 760 mmHg
- 闪点：
- 341.3ºC
- 折射率：
- 1.596
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DF6845120
- CHEMICAL NAME :
- 5-Benzofuranmethanol, 4,7-dimethoxy-alpha-(2-(4-hydroxyphenyl)ethyl)-6- (2-(1-piperidinyl)ethoxy)-
- CAS REGISTRY NUMBER :
- 40680-87-3
- BEILSTEIN REFERENCE NO. :
- 1276232
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C26-H33-N-O6
- MOLECULAR WEIGHT :
- 455.60
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 420 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JNPHAG Journal de Pharmacologie. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1970- Volume(issue)/page/year: 8,125,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 9900 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,85,1974
