5,12-Naphthacenedione,8-acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-,(8S,10S)-
- 中文别名：洋红霉素
- 中文释义：卡米诺霉素;洋红霉素
- 英文别名：5,12-Naphthacenedione, 8-acetyl-10-[[3-amino-2,3,6-trideoxy-.α.-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, (8S-cis)-;
Antibiotic R-588A;
carminomycin I;
Karminomitsin;
Carminomicin I;
Carubicin;
(8S-cis)-Acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-5,12-naphthacenedione
- CAS No.：50935-04-1
- 分子式：C26H27NO10
- 分子量：513.54
- 精确分子量：513.16300
- PSA：196.84000
- InChI：The Key: XREUEWVEMYWFFA-ARMZNTOKSA-N
- 分子结构式：
物化性质
- 密度：
- 1.63g/cm3
- 沸点：
- 750.6ºC at 760mmHg
- 闪点：
- 407.7ºC
- 折射率：
- 1.726
- 存储条件/存储方法：
- 库房低温通风干燥,与食品原料分开存放
安全信息
- 密度：
- 1.63g/cm3
- 沸点：
- 750.6ºC at 760mmHg
- 闪点：
- 407.7ºC
- 折射率：
- 1.726
- 存储条件/存储方法：
- 库房低温通风干燥,与食品原料分开存放
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QI9293250
- CHEMICAL NAME :
- 5,12-Naphthacenedione, 8-acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hex opyranosyl)oxy)- 7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, (8S-cis)-
- CAS REGISTRY NUMBER :
- 50935-04-1
- LAST UPDATED :
- 199406
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C26-H27-N-O10
- MOLECULAR WEIGHT :
- 513.54
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7250 ug/kg
- TOXIC EFFECTS :
- Behavioral - tremor Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1100 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3800 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3400 ug/kg
- TOXIC EFFECTS :
- Behavioral - tremor Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Rodent - mouse Leukocyte
- DOSE/DURATION :
- 490 nmol/L
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 34,1596,1981
