dimetindene
- 中文别名：二甲茚定
- 中文释义：二甲茚定;吡啶茚胺
- 英文别名：N,N-dimethyl-2-[3-(1-pyridin-2-ylethyl)-1H-inden-2-yl]ethanamine;
Triten;
Dimethpyrindene;
Dimetindeno;
N,N-dimethyl-3-[1-(2-pyridyl)ethyl]inden-2-ethylamine;
Dimetindene;
dimethyl-{2-[3-(1-pyridin-2-yl-ethyl)-inden-2-yl]-ethyl}-amine;
Pecofenil;
dimethindene;
Dimetindenum;
Foristal;
Fenistil;
Forhistal
- CAS No.：5636-83-9
- 分子式：
C20H24N2
- 分子量：292.42
- 精确分子量：292.19400
- PSA：16.13000
- InChI：The Key: MVMQESMQSYOVGV-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.065 g/cm3
- 沸点：
- 416.3ºC at 760 mmHg
- 闪点：
- 205.6ºC
- 折射率：
- 1.587
安全信息
- 密度：
- 1.065 g/cm3
- 沸点：
- 416.3ºC at 760 mmHg
- 闪点：
- 205.6ºC
- 折射率：
- 1.587
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UT0800000
- CHEMICAL NAME :
- Pyridine, 2-(1-(2-(2-(dimethylamino)ethyl)inden-3-yl)ethyl)-
- CAS REGISTRY NUMBER :
- 5636-83-9
- BEILSTEIN REFERENCE NO. :
- 0489974
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C20-H24-N2
- MOLECULAR WEIGHT :
- 292.46
- WISWESSER LINE NOTATION :
- L56 BHJ C2N1&1 DY1&- BT6NJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 618 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973 Volume(issue)/page/year: -,95,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 27 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973 Volume(issue)/page/year: -,95,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 45 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973 Volume(issue)/page/year: -,95,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 888 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973 Volume(issue)/page/year: -,95,1973
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